Samstag 8. März 2014, 10:19
World J Gastroenterol. 2014 March 7; 20(9): 2159-2167.
Published online 2014 March 7. doi: 10.3748/wjg.v20.i9.2159.
Pharmacotherapy of acute alcoholic hepatitis in clinical practiceLudovico Abenavoli, Natasa Milic, Samir Rouabhia and Giovanni Addolorato.
Core tip: The therapy of severe alcoholic hepatitis (AH) is a problem in clinical practice due to the complex of the pathogenetic mechanisms involved. However, several treatment options are now available. The specific treatment of AH is directed to acute injury in order to block the progression of the fibrosis. Orthotopic liver transplantation is a possible therapeutic option for severe AH in the non-responder patients. Baclofen seems to be effective and safe anti-craving drug able to improve abstinence in patients with severe AH.